Friday, July 4, 2008

A summary of a experimental research paper

Source from http://breast-cancer-research.com/content/8/2/R14

Research article: Breast asymmetry and predisposition to breast cancer

Medical Research is common to use different case studies for comparison and analysis. After having the data collection, data will be analyzed, so to make a medical statistics and further studying. Testing for each individual case is needed, such as this research article. It is mainly focus on comparison of the diagnosed breast cancer with more breast volume asymmetry,as measured from mammograms,patients and age-matched healthy women.

Also, this was a retrospective study on women who had mammography during the period 1979 to 1986. The original study collected detailed breast cancer risk factor data form a total of 12942 women self-referred to the Liverpool Breast Screening Unit between 1979 and 1986, the aim being to establish whether mammographic parenchymal patterns were associated with hypothesised risk factors for breast cancer.

For this research study, a study group and a control group were formed to compare two streams of cases. The study group consisted of 252 asymptomatic women who had normal mammography, but went on to develop breast cancer. The control group consisted of 252 age-matched healthy controls whose mammograms were also normal and who remained free of cancer during the study period.

For each group, breast volume was calculated from the cranio-caudal mammograms. Thus the relationships between asymmetry will establish risk factors and the presence or absence of breast cancer were explored. If the breast asymmetry was greater in healthy women who later developed breast cancer than in women who did not.

After having the results, there will have some discussion for the findings, and a brief conclusion to sum up the findings.


2 comments:

Allen said...

Thanks Iris for posting the article for our discussion. I have a different view on the research method classification. It seems to me that this one belongs to quantitative research more than qualitative. The researchers were collecting data from a relatively large sample and then calculate the correlation between the data, hoping to discover a relationship between variables.

It is a healthy discussion. Welcome for further comments.

方潤 said...

Agree to Allen.
But this is a very interesting paper. :)

I think this could be a kind of correlation study, research is going to find a correlation between breast asymmetry and the development of breast cancer.